Internal Reference Number: FOI_8035
Date Request Received: 08/07/2024 00:00:00
Date Request Replied To: 15/07/2024 00:00:00
This response was sent via: By Email
Request Summary: Diffuse Large B Cell Lymphoma (DLBCL)
Request Category: Private Individuals
| Question Number 1: In the last 6 months, how many patients have been diagnosed with Diffuse Large B Cell Lymphoma (DLBCL)? 1a. Of these patients, how many commenced treatment at your trust within the last 6 months? | |
| Answer To Question 1: 1. 7 patients have been diagnosed with Diffuse Large B Cell Lymphoma. 1a. 6 of the 7 patients diagnosed were treated within the last six months. | |
| Question Number 2: In the last 6 months, how many patients have you treated for Diffuse Large B Cell Lymphoma (DLBCL) with the following treatments: R-CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine and prednisolone) R-mini-CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine and prednisolone) Pola-BR (polatuzumab vedotin with rituximab and bendamustine) Pola-R-CHP (Polatuzumab vedotin with rituximab, cyclophosphamide, doxorubicin hydrochloride, and prednisolone) R-CODOX-M (rituximab, cyclophosphamide, vincristine, doxorubicin and methotrexate) R-IVAC (rituximab, ifosfamide, etoposide and cytarabine) Axicabtagene ciloleucel (Yescarta) Tisagenlecleucel Epcoritamab Loncastuximab tesirine Glofitamab Any other SACT Stem cell transplant or bone marrow transplant (autologous or allogeneic) | |
| Answer To Question 2: -CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine and prednisolone) <5 patients. R-mini-CHOP (rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine and prednisolone) <5 patients Pola-BR (polatuzumab vedotin with rituximab and bendamustine) <5 patients Pola-R-CHP (Polatuzumab vedotin with rituximab, cyclophosphamide, doxorubicin hydrochloride, and prednisolone) 6 patients R-CODOX-M (rituximab, cyclophosphamide, vincristine, doxorubicin and methotrexate) 0 patients R-IVAC (rituximab, ifosfamide, etoposide and cytarabine) 0 patients Axicabtagene ciloleucel (Yescarta) 0 patients Tisagenlecleucel 0 patients Epcoritamab <5 patients Loncastuximab tesirine 0 patients Glofitamab 0 patients Any other SACT <5 patients Stem cell transplant or bone marrow transplant (autologous or allogeneic) - These are referred to UHS - please contact Southampton for information if required: freedomofinformation@uhs.nhs.uk | |
| Question Number 3: In the last 6 months, how many patients have received the following 2nd line treatments for Diffuse Large B Cell Lymphoma (DLBCL): Axicabtagene ciloleucel (Yescarta) Tisagenlecleucel Pola-BR (polatuzumab vedotin with rituximab and bendamustine) Stem cell transplant or bone marrow transplant (autologous or allogeneic) Any other treatments | |
| Answer To Question 3: Axicabtagene ciloleucel (Yescarta) Tisagenlecleucel 0 patients Pola-BR (polatuzumab vedotin with rituximab and bendamustine) <5 patients Stem cell transplant or bone marrow transplant (autologous or allogeneic) Not currently being done on site. 0 patients. These are referred to UHS - please contact Southampton for information if required: freedomofinformation@uhs.nhs.uk Any other treatments <5 | |
| Question Number 4: In the last 6 months, how many patients have you referred to other trusts for the treatment of Diffuse Large B Cell Lymphoma (DLBCL) for the following treatments: CAR-T Therapy (E.g. Axicabtagene ciloleucel) Stem cell transplant or bone marrow transplant (autologous or allogeneic) Any other treatment | |
| Answer To Question 4: CAR-T Therapy (E.g. Axicabtagene ciloleucel) <5 Stem cell transplant or bone marrow transplant (autologous or allogeneic) These are referred to UHS - please contact Southampton for information if required: freedomofinformation@uhs.nhs.uk Any other treatment - CNS DLBCL <5 patients | |
| Question Number 5: Do you participate in any active clinical trials for Diffuse Large B-Cell Lymphoma (DLBCL)? If so, can you please provide the name of each trial along with the number of patients taking part or enrolling? | |
| Answer To Question 5: No active DLBCL trials at present | |
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